Dyshidrotic eczema (pompholyx)

Dyshidrotic eczema (pompholyx)

Numerous causes for dyshidrotic eczema (also known as pompholyx) have been suggested. Contact allergy is an underlying cause in two-thirds of patients, most frequently due to nickel, chromium, shower gel and shampoo.22 A personal and/or family history of atopy has been reported in 50% of patients. The condition may be aggravated by changes in ambient temperature, humidity, excessive sweating and emotional stress.23

Pompholyx is associated with intensely itchy cysts or deep-seated fluid-filled blisters.23 Lesions are most often present on the palms of the hands but can also occur on the soles of the feet, or both.22 There is typically thickening of the epidermis and fluid accumulation.23

Dyshidrotic eczema

Image source: DermnetNZ

The majority of pompholyx cases occur between the ages of 30 and 40 years,22 and it accounts for approximately 15% of hand eczema cases.24


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UK/GEN/16/0051 Date of preparation: October 2016