It has been estimated that of children aged under 18 years with atopic eczema, around 30-50% will experience persistent disease into adulthood.1-3 The presence of factors such as sensitisation and parental history of atopy significantly increase the likelihood of eczema persistence.3
Although atopic eczema is typically the first manifestation of atopy in early life, many people progress to having other allergies in later life, including asthma and allergic rhinitis - this has been called the "allergic march"4.
- Garmhausen D, Hagemann T, Bieber T et al. Characterization of different courses of atopic dermatitis in adolescent and adult patients. Allergy 2013;68:498--506.
- Mortz CG, Andersen KE, Dellgren C et al. Atopic dermatitis from adolescence to adulthood in the TOACS cohort: prevalence, persistence and comorbidities. Allergy 2015;70:836--45.
- Peters AS, Kellberger J, Vogelberg C et al. Prediction of the incidence, recurrence, and persistence f atopic dermatitis in adolescence: a prospective cohort study. J Allergy Clin Immunol 2010;126:590--5.
- Spergel JM. From atopic dermatitis to asthma: the atopic march. Ann Allergy Asthma Immunol 2010;105:99--106.
UK/GEN/16/0051 Date of preparation: October 2016